
A new study reports that antibiotic use during pregnancy is associated with an increased risk for obesity in the child.
Researchers studied 436 mothers and their children from birth until age seven, gathering data on antibiotic use from interviews.
After controlling for gestational age,
birth weight, breast-feeding, maternal body mass index and socioeconomic
status, among other variables, they found that antibiotic use during
the second and third trimesters was associated with an 84 per cent
increased risk for obesity in the child.
The study, published in the International
Journal of Obesity, also found that cesarean section was associated
with a 46 per cent increased risk for obesity in the offspring,
confirming previous studies.
The authors acknowledge that they had no
data on which antibiotics were administered or for what infections,
factors that could have affected their results.
The mechanism is unclear, and the study
shows only an association, but the lead author, Noel T. Mueller, a
postdoctoral research fellow at Columbia University, suggested that the
prenatal exchange of antibiotics between mother and child may affect the
colonisation of bacteria in the newborn’s gut.
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